One night after a particularly bad loss in one of my startups, I came home and my wife said, in what she meant to be reassuring but felt crushing at the time, “at least you’re a great dad.”
Tag Archives: Startups
In Defense of Effective Altruism
The Worst Form of Ethics, Except For All The Others This would’ve been a lot easier in August 2022. Flash forward 15 months, and the EA movement is in trouble. RIP: Effective Altruism (2011-2023). Right? “The measure of a man’s life is not the number of his breaths, but the action he takes.” – AristotleContinue reading “In Defense of Effective Altruism”
Biotech 2.0
Biotech is following the same technological revolution roadmap as the internet, just 20-30 years later. It’s time to prepare for Biotech 2.0 now.
End Accredited Investor Laws
90% of Americans can’t invest in startups. Let’s change that now. Idea: Eliminate all accredited investor restrictions for startups and VC funds.
How I’d Invest a $1B+ Fund
Why investing early-stage at scale is the best opportunity in VC now. Idea: Be the first investor and advisor to thousands of early-stage startups.
Scientist CEOs
Helping elite scientists become elite startup founders Trend: Silicon Valley now celebrates the technical founder CEO. Myth: Most VCs still think that scientists can’t be good CEOs. How: Be the first investor and advisor for startups led by scientist CEOs. Opportunity: Elevating scientist CEOs is good for everyone. This idea is a work-in-progress. If you’dContinue reading “Scientist CEOs”
Y Combinator for Biotech
Bringing the original YC model to biotech. Introduction: Both of these VC models are built for the old playbook for biopharma company formation: Two big changes have made it much cheaper to launch and scale biotech companies: The new playbook for biotech will be the YC fundraising model, as explained by Paul Graham: Biotech isContinue reading “Y Combinator for Biotech”
Stay in the Pocket
Imagine you’re a quarterback. The center snaps the ball to you. Look up. Take three steps back. Two defenders are coming through the line, one on each side. Pause. What do you do next? Everything in your body tells you to run, escape. You want to get out of the pocket. But the right moveContinue reading “Stay in the Pocket”
It’s 1994 Again
We are in the dot-com era for biotech. Introduction: For the last 25+ years, we have been living through one of the greatest technological revolutions ever, the Information Age. From Web 1.0 to Web 2.0 to Mobile to Web 3.0, the best startup founders and investors have ridden these waves to impact billions of peopleContinue reading “It’s 1994 Again”
The Front Door
We Need A YC for Everything This is Problem #3 on my list of The World’s Biggest Problems.