The Y Combinator Era for Biotech

YC is now focused on biotech. Will VCs follow? Introduction: Both of these VC models are built for the old playbook for biopharma company formation: Two big changes have made it much cheaper to launch and scale biotech companies: The new playbook for biotech will be the YC fundraising model, as explained by Paul Graham:Continue reading “The Y Combinator Era for Biotech”

It’s 1994 Again

We are in the dot-com era for biotech. Introduction: For the last 25+ years, we have been living through one of the greatest technological revolutions ever, the Information Age. From Web 1.0 to Web 2.0 to Mobile to Web 3.0, the best startup founders and investors have ridden these waves to impact billions of peopleContinue reading “It’s 1994 Again”

The Front Door

We Need A YC for Everything This is Problem #3 on my list of The World’s Biggest Problems. The short answer is you need to know somebody. If you don’t already know one of them, you’re not getting in the front door. Those who do break through without connections take a grueling path to success,Continue reading “The Front Door”

YC for Politics

An accelerator for rising stars in politics Create a new front door for politics and government. YC did this for VC. This has massively increased the pool of potential startup founders. We can create a YC-like path for less privileged people to become politicians. Network and fundraise from the Democratic or Republican establishment. This systemContinue reading “YC for Politics”

Effective Immigration

This is Solution #6 on my list of The World’s Biggest Problems. Introduction Increasing immigration is one of the best forms of effective altruism. Each 1% rise in the labor force through increased immigration leads to $100B in gains for immigrants and $17B in net benefits for host countries. This is more than the $70BContinue reading “Effective Immigration”

The Money Problem

Money vs. Meaning Everyone has a number where they’d be financially ‘free’. The gap between this number and your current wealth is your money problem. Most people would quit if they had $100K+ to cover their next 1-2 years. This is Personal Capital. Many people need $10K or less to start their passion project. See:Continue reading “The Money Problem”

Y Combinator for Mittelstands

Both of these ideas are on my list of solutions to The World’s Biggest Problems. DM or email me if you want to invest! Summary: Accelerator: Invest the first $100K+ to help new pre-Mittelstands launch and grow. Ventures: Invest $1M+ to help pre-Mittelstands go from $1M to $10M+ revenue. Most VCs won’t fund niche servicesContinue reading “Y Combinator for Mittelstands”

We Need A Middle Class For Startups

Bootstrapped from zero. “Sell a product or course online! Sell services locally!” There are millions of different get rich quick schemes floating online now. The goal here is to secure the bag and escape the grind ASAP. Raised $100M+ from VCs. “Are you a Unicorn yet? Which Y Combinator class were you in?” Startups areContinue reading “We Need A Middle Class For Startups”

The Decades Are Short But The Centuries Are Long

Labdoor is turning 10 years old this month! We’ve been through so much — moving cross-country to SF to join Rock Health, raising a seed round led by Mark Cuban, creating a passionate community of smart consumers, getting accepted into Y Combinator’s Winter 2015 class, fighting multiple lawsuits from supplement companies, raising a Series A ledContinue reading “The Decades Are Short But The Centuries Are Long”