The World's Biggest Problems

An Effective Altruist‘s Guide to New Ideas

These are my rankings of the world’s top 20 problems and 100 potential solutions.

Three of my startups, Utopic, Labdoor, and Air to All, are based on these ideas.
- I want to invest my time, money, and passion into all 100 solutions in my lifetime.

I’m writing one chapter on each of these 120+ ideas. This will be a book when it’s all done!

See: Table of Contents
Status: 39 of 120+ chapters complete!

Our mission is to solve all of these world’s biggest problems together!

There are way too many important problems in the world for any one person to solve.
I’m sharing these ideas so we can get more people organized around all of these problems!

Are you working on one of these problems or solutions? I want to talk with you!

Tweet or DM me @neilthanedar and tell me what you’re building!
I’m writing this book in public to inspire more people to work on these problems together transparently.

Solution #1: Effective Altruism
- Book: The World’s Biggest Problems
Solution #2: Founder Accelerator
- Idea: Utopic Ventures
Solution #3: Personal Capital
- Startup: Utopic Studio
Solution #4: Disrupt Venture Capital
- Idea: How I’d Invest a $1B+ Fund
Solution #5: ISAs for Everything
- Idea: UMICH 2050

Problem #2: Ambition

Solution #6: Effective Immigration
Solution #7: Ambitious Optimists
- Idea: Utopic Live
Solution #8: Everyday Activism
Solution #9: Nonprofit Startups
Solution #10: YC for Nonprofits
- Idea: Utopic Foundation

Problem #3: Access

Solution #11: Startup Investing for All
- Idea: End Accredited Investor Laws
Solution #12: Open Patents
Solution #13: Open Access Movement
Solution #14: OpenAI for Data
Solution #15: Decentralized Banking

Problem #4: Abundance

Solution #16: Pro-Growth Progressives
- Idea: Abundance Age nda (Derek Thompson)
- Idea: A Liberalism That B uilds (Ezra Klein)
Solution #17: Public Manufacturing
- Idea: Let The Government Manufacture Generic Drugs (Elizabeth Warren)
- Idea: Universal Food Security
Solution #18: Legalize All Housing
Solution #19: YC for Manufacturing
Solution #20: Arsenal of Progress
- Idea: Detroit vs. Shenzhen

Problem #5: Attention

Solution #21: Real Real GDP
Solution #22: Long-Term News
Solution #23: Independent Auditors
Solution #24: Build A Third Brain
Solution #25: Open Metaverse

Problem #6: Freedom

Solution #26: Cryptocountries
Solution #27: DAOs for Everything
Solution #28: Zero-Knowledge Services
Solution #29: The Rise of Pseudonyms
Solution #30: Distributed Internet

Problem #7: Authoritarianism

Solution #31: AI Alignment
Solution #32: Unbundle The Police
Solution #33: Civil Justice Reforms
Solution #34: Satyagraha Club
Solution #35: Pax Internet

Problem #8: Politics

Solution #36: Fight The Two-Party System
- Idea: Abolish The Electoral College
- Idea: End Gerrymandering
- Idea: Ranked-Choice Voting
Solution #37: Independents Movement
- Idea: We Need An Alternative to Political Parties
Solution #38: Open Campaign Finance
- Idea: Public Campaign Financing
- Idea: OpenSecrets for All Spending
Solution #39: YC for Politics
Solution #40: Make Voting Public
- Idea: Cryptographic Voting

Problem #9: Government

Solution #41: New Efficiency Movement
- Idea: How to Fix the FDA
Solution #42: End Regulatory Capture
- Idea: Open Public Contracts
Solution #43: Public Ventures
- Idea: 43North for Detroit
Solution #44: Digital Dollars
Solution #45: New Bill of Rights

Problem #10: Science

Solution #46: YC for Biotech
Solution #47: Scientist CEOs
Solution #48: Biotech 2.0
Solution #49: The Next Genentech
Solution #50: OpenAI for Science

Problem #11: Environment

Solution #51: Pro-Social Environmentalism
Solution #52: Commodify Detoxification
- Idea: Carbon Removal
- Idea: Commodify Desalination
Solution #53: Petrochemical Alternatives
Solution #54: Play Defense on Earth
- Idea: Defend Arctic Ice Sheet
- Idea: Protect Amazon Rainforest
- Idea: Clean Up Great Lakes
Solution #55: Expand Into Outer Space
- Idea: Space Manufacturing

Problem #12: Energy

Solution #55: Moore’s Law for Everything
- Idea: Keep Commodifying Solar
- Idea: Keep Commodifying Batteries
Solution #56: Normalize Elemental Energy
- Idea: Commodify Nuclear Fusion
Solution #58: Reinvent Appliances
- Idea: Modern HVAC
- Idea: Electric Kitchen
Solution #59: Decentralize Utilities
Solution #60: Commodify Energy
- Idea: Electricity Too Cheap To Meter

Problem #13: Education

Solution #61: Universal Preschool
Solution #62: Montessori K-12 Schools
Solution #63: Microschool Platforms
Solution #64: Full-Stack Schools
Solution #65: MOOCs for Everything

Problem #14: Healthcare

Solution #66: Universal Healthcare
Solution #67: Nonprofit Therapeutics
- Startup: Air to All
Solution #68: Decentralized Clinical Trials
Solution #69: Personalized Medicine
Solution #70: Consumer Diagnostics

Problem #15: Depression

Solution #71: Hyperthymic Antidepressants
Solution #72: Trusted Therapy Network
Solution #73: Secure Firearms
Solution #74: AA for Everything
Solution #75: AI as Companion

Problem #16: Safety

Solution #76: Decentralized FDA
Solution #77: Independent Testing
- Startup: Labdoor
Solution #78: Crypto Certifications
- Idea: TEST
Solution #79: Ban Carcinogens
Solution #80: Ban Endocrine Disruptors

Problem #17: Mittelstands

Solution #81: Indie Startups
Solution #82: YC for Mittelstands
Solution #83: Seed-Stage Private Equity
Solution #84: 0% Interest Business Loans
Solution #85: Fractionalize Everything

Problem #18: Peace

Solution #86: Global Biosecurity
Solution #87: International Peace Corps
Solution #88: Sanctuary Countries
Solution #89: Legalize Psychedelics
Solution #90: Utopiaforming

Problem #19: History

Solution #91: Recreate Ancient Foods
Solution #92: Modern Ethnobiology
Solution #93: Record All Languages
Solution #94: Record Many Histories
Solution #95: Open World Library

Problem #20: Exploration

Solution #96: Commodify Space Travel
Solution #97: New ISS
Solution #98: New Hubble
Solution #99: Map Our Universe
Solution #100: ISS Enterprise

The World’s Biggest Problems